Merkel cell tumor. A chemosensitive skin cancer
نویسندگان
چکیده
منابع مشابه
Merkel cell cancer of the skin.
Merkel cell carcinoma (MCC) is a rare malignant cutaneous tumor of the elderly with rapidly growing skin nodules found predominantly on sun-exposed areas of the body. The vast majority of patients present with localized disease, while up to 30% have regional lymph node metastases. Despite local excision and the incidence of local recurrence, regional lymph node metastases and distant metastases...
متن کاملMerkel cell carcinoma of the skin.
Primary neuroendocrine carcinoma of the skin or Merkel cell carcinoma is an aggressive primary neoplasm. It is commonly seen in the elderly, on the head, neck and extremities, where it can mimic a benign or less malignant skin tumour. Pathological examination shows a generally dense growth of small dark cells, with immunohistochemical evidence of neuroendocrine differentiation. The microscopic ...
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This case of a Merkel cell carcinoma is unusual due to the occurrence of the tumor on the thigh; most Merkel cell tumors have been found on the sun-exposed region of the head and neck. Histologically, the nodule was composed of sheets of uniform, poorly differentiated cells with a high nuclear to cytoplasmic ratio. Electron microscopy revealed perinuclear filaments, scattered dense core granule...
متن کاملMerkel cell tumor of the skin treated with localized radiotherapy: are widely negative margins required?
Merkel's cell carcinoma is a rare cutaneous tumor that can affect a wide variety of sites throughout the body. Commonly, it affects the skin alone and the management of limited disease can be confusing since the natural history of the disease involves distant metastasis. Traditional management has required wide local excision with negative margins of resection. We describe a case treated with l...
متن کاملmerkel cell polyomavirus infection in a patient with merkel cell carcinoma: a case report
conclusions the findings of this study are consistent with the hypothesis that local, systemic, or tumor-induced immunosuppression may allow the mcpyv to initiate skin aggressive cancer. it is necessary to maintain regular check over patients taking immunosuppressive medications for mcpyv infection. since there is not any information about detection and molecular biology analysis of mcpyv among...
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ژورنال
عنوان ژورنال: Cancer
سال: 1988
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19880701)62:1<28::aid-cncr2820620107>3.0.co;2-j